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Ten U.S. Patents Issued for STC.UNM Technologies in 3rd Quarter

Albuquerque, NM – April 1, 2015 The U.S. Patent & Trademark Office (USPTO) recently issued 10 patents during January, February and March for technologies invented at the University of New Mexico. The 10 patents, issued during STC.UNM’s 2015 fiscal 3rd quarter, are for a variety of technologies created by researchers in the Department of Electrical & Computer Engineering, Center for High Tech Materials, Department of Chemical & Nuclear Engineering, Center for Micro-Engineered Materials, Department of Biochemistry & Molecular Biology, and the College of Pharmacy.

Issued Patent for: “Multi Comb Generation with a Mode Locked Laser Cavity”
Patent No. 8,929,408, issued January 6, 2015
Inventors: Jean-Claude Diels, Ladan Arissian, Koji Masuda

Apparatus, systems, and methods of generating multi combs can be used in a variety of applications. In various embodiments, an etalon can be disposed in the laser cavity of a mode-locked laser to adjust frequency combs. Additional apparatus, systems, and methods are disclosed.

Issued Patent for: “Selective Epitaxial Overgrowth Comprising Air Gaps”
Patent No. 8,937,366, issued January 20, 2015
Inventors: Sang Han, Darin Leonhardt, Swapnadip Ghosh

This technology is a novel method to mitigate the stress induced by thermal expansion coefficient mismatch for semiconductor devices. A SiO2 nanotemplate structure is used to block the threading dislocations and reduce the thermal stress due to thermal expansion coefficient mismatch between Ge and Si. Unlike thermally grown SiO2, these SiO2 templates, inserted within the Ge layer by chemical vapor deposition and conventional dry etching, leave voids around the template sidewall and top surface, while allowing Ge to grow selectively over the template surface and relax. These voids (or air-gap) around the template sidewalls and top surface relieve stress caused by the thermal expansion coefficient mismatch between the film and the substrate. Potential applications include near-infrared photodetectors, high-mobility field effect transistors, virtual substrates for integrating III-V multijunction solar cells, and other semiconductor devices.

Issued Patent for: “Oxygen Side Electrode for a Fuel Cell”
Patent No. 8,945,791, issued February 3, 2015
Inventors: Koichiro Asazawa, Koji Yamada, Hirohisa Tanaka, Kazuya Yamamoto, Tim Olson, Svitlana Pylypenko, Plamen Atanassov

In a fuel cell including an electrolyte layer allowing an anion component to migrate, and a fuel-side electrode and an oxygen-side electrode arranged to face each other while sandwiching the electrolyte layer, the oxygen-side electrode contains a first catalyst containing a first transition metal and polypyrrole, and a second catalyst containing a second transition metal and a porphyrin ring-containing compound so that the mixing ratio of the first catalyst relative to 100 parts by mass of the total amount of the first catalyst and the second catalyst is more than 10 parts by mass, and below 90 parts by mass.

Issued Patent for: “Solid-State Microscope for Selectively Imaging a Sample”
Patent No. 8,964,020, issued February 24, 2015
Inventor: Stephen D. Hersee

Exemplary embodiments provide solid-state microscope (SSM) devices and methods for processing and using the SSM devices. The solid-state microscope devices can include a light emitter array having a plurality of light emitters with each light emitter individually addressable. During operation, each light emitter can be biased in one of three operating states including an emit state, a detect state, and an off state. The light emitter can include an LED (light emitting diode) including, but not limited to, a nanowire-based LED or a planar LED to provide various desired image resolutions for the SSM devices. In an exemplary embodiment, for near-field microscopy, the resolution of the SSM microscope can be essentially defined by the pitch p, i.e., center-to-center spacing between two adjacent light emitters, of the light emitter array.

Issued Patent for: “Synthesis of Pd Particles by Alcohols-Assisted Photoreduction for Use in Supported Catalysts”
Patent No. 8,962,512, issued February 24, 2015
Inventors: Patrick Burton, Timothy Boyle, Abhaya Datye

The present disclosure provides a novel synthesis method for palladium nanoparticles and palladium nanoparticles made using the method. The nanoparticles resulting from the method are highly reactive and, when deposited on a support, are highly suitable for use as catalytic material.

Issued Patent for: “Methods and Systems for Dosing and Coating Inhalation Powders Onto Carrier Particles”
Patent No. 8,962,063, issued February 24, 2015
Inventors: Hugh D.C. Smyth and Martin J. Donovan

A method of coating powdered medical agent onto a carrier particle for use in a dry powder inhaler may include applying ultrasonic energy to agglomerated powdered medical agent to de-aggregate and aerosolize particles of the medical agent into particles having a desired average particle size, and coating at least one carrier particle with a desired amount of the de-aggregated and aerosolized particles of the medical agent.

Issued Patent for: “Substituted Cis- and Trans-Stilbenes as Therapeutic Agents”
Patent No. 8,980,954, issued March 17, 2015
Inventors: David Vander Jagt and Lorraine Deck

The present invention relates to method(s) of treating a subject afflicted with cancer or a precancerous condition, an inflammatory disease or condition, and/or stroke or other ischemic disease or condition, the method comprising administering to the subject or patient in need a composition comprising a therapeutically effective amount of a substituted cis- or trans-stilbene.

Issued Patent for: “Selective Nanoscale Growth of Lattice Mismatched Materials”
Patent No. 8,980,730, issued March 17, 2015
Inventors: Seung-Chang Lee and Steven R.J. Brueck

Exemplary embodiments provide materials and methods of forming high-quality semiconductor devices using lattice-mismatched materials. In one embodiment, a composite film including one or more substantially-single-particle-thick nanoparticle layers can be deposited over a substrate as a nanoscale selective growth mask for epitaxially growing lattice-mismatched materials over the substrate.

Issued Patent for: “Compounds with Reduced Ring Size for Use in Diagnosing and Treating Melanoma, Including Metastatic Melanoma and Methods Related to Same”
Patent No. 8,986,651, issued March 24, 2015
Inventors: Yubin Miao and Haixun Guo

The present invention is directed to novel noninvasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using noninvasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as for monitoring patients’ response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.

Issued Patent for: “Protocells and Their Use for Targeted Delivery of Multicomponent Cargos to Cancer Cells”
Patent No. 8,992,984, issued March 31, 2015
Inventors: C. Jeffrey Brinker, Carlee Erin Ashley, Xingmao Jiang, Juewen Liu, David S. Peabody, Walker Richard Wharton, Eric Carnes, Bryce Chackerian, Cheryl L. Willman

Various embodiments provide materials and methods for synthesizing protocells for use in targeted delivery of cargo components to cancer cells. In one embodiment, the lipid bilayer can be fused to the porous particle core to form a protocell. The lipid bilayer can be modified with targeting ligands or other ligands to achieve targeted delivery of cargo components that are loaded within the protocell to a target cell, e.g., a type of cancer. Shielding materials can be conjugated to the surface of the lipid bilayer to reduce undesired nonspecific binding.

Source: USPTO

For more information, contact:

Denise Bissell
dbissell@stc.unm.edu